In the ever-evolving world of skincare, ingredient trends come and go—but a few gold-standard actives continue to dominate dermatologists’ shelves and treatment rooms. At Clarísima, we don’t chase trends—we study them, test them, and only embrace the ingredients that deliver real, visible transformation.
Here are the Top 5 Dermatologist-Approved Ingredients you’ll find across our Clarísima formulas—and why they’re essential for healthy, radiant skin.
1. PDRN (Sodium DNA): The Regeneration Molecule
What it is:
PDRN (Polydeoxyribonucleotide) is derived from salmon DNA and has powerful skin-repairing and anti-inflammatory properties. It stimulates tissue regeneration by activating the A2A adenosine receptors—this leads to increased cell turnover, collagen production, and healing.
Why dermatologists love it:
- Boosts post-procedure recovery
- Improves elasticity and texture
- Reduces inflammation and signs of aging
- Ideal for sensitive, damaged, or mature skin
Where you’ll find it in Clarísima:
👉 PDRN + HA Booster
A regenerative injectable skin booster combining 2% Sodium DNA with 0.25% Hyaluronic Acid and Niacinamide for hydration and repair.
2. EGF (Epidermal Growth Factor): Skin Cell Whisperer
What it is:
EGFs are proteins that signal your skin cells to divide, regenerate, and repair. They’re naturally present in our skin but decrease with age, leading to slower healing and dullness.
Why dermatologists love it:
- Stimulates collagen and elastin
- Speeds up wound healing
- Smooths fine lines and brightens skin
- Enhances skin’s overall resilience
Where you’ll find it in Clarísima:
👉 Cellaris EGF Booster
A high-potency serum packed with EGF, peptides, and antioxidants—ideal for post-laser recovery or aging skin support.
3. Hyaluronic Acid (HA): The Moisture Magnet
What it is:
HA is a sugar molecule naturally found in skin that binds up to 1,000 times its weight in water, keeping skin plump, smooth, and hydrated.
Why dermatologists love it:
- Restores hydration from within
- Plumps fine lines instantly
- Improves skin barrier and elasticity
- Safe and effective for all skin types, even post-procedure
Where you’ll find it in Clarísima:
👉 HA-Peptide Fusion Skin Booster
A powerhouse formula with multi-molecular HA and over 50 active ingredients including peptides, amino acids, and coenzymes.
👉 Soothing Barrier Creams & Gels
Like our Panthenol + Centella gel for post-laser hydration and calming.
4. Ectoin®: The Cellular Shield
What it is:
Ectoin is a stress-protection molecule found in microorganisms that live in extreme environments (like salt lakes or deserts). It protects skin cells from damage caused by UV rays, pollution, blue light, and dehydration.
Why dermatologists love it:
- Reinforces the skin barrier
- Protects DNA from oxidative stress
- Soothes inflammation and sensitivity
- Ideal for urban, reactive, or over-treated skin
Where you’ll find it in Clarísima:
👉 Night Repair Skin Cream
Blends Ectoin with Squalane, Retinol, Ceramides, and Glycolic Acid to repair skin overnight without triggering irritation.
5. Niacinamide (Vitamin B3): The Multitasking Hero
What it is:
Niacinamide is a form of Vitamin B3 with proven ability to brighten, soothe, strengthen, and protect the skin. It’s one of the most versatile ingredients in dermatology.
Why dermatologists love it:
- Reduces redness and blotchiness
- Fades dark spots and pigmentation
- Minimizes pores and regulates sebum
- Enhances barrier repair and elasticity
Where you’ll find it in Clarísima:
👉 Skin Boosters (PDRN + HA Booster)
👉 Barrier Repair Creams
👉 Post-Laser Serums
Especially useful after treatments like microneedling or resurfacing.
✨ Bonus Trend: Peptides and Nucleotides Are the New Anti-Aging Power Duo
While not technically part of the “top 5,” dermatologists are increasingly turning to bioactive peptides and DNA-based ingredients (like nucleotides) for smarter skin aging solutions. That’s why Clarísima includes:
- Tripeptides and Tetrapeptides – to relax expression lines and stimulate collagen
- Nucleotides – for energy, cell repair, and tissue renewal
These are all included in our HA-Peptide Fusion and Cellaris lines for maximum synergistic effect.
Final Thoughts: Your Skin Deserves Clinical Care, Not Just Beauty Buzzwords
At Clarísima, we formulate with respect for your skin’s biology and with ingredients that dermatologists actually trust and use. Our mission is to bring you high-performance products that deliver results—whether you’re using them at home or in a professional setting.
🔬 Science-backed. 🌿 Nature-inspired. 💧 Skin-transforming.
